The legacy of Edward Jenner
- 11 May 1996
- Vol. 312 (7040) , 1177-1178
- https://doi.org/10.1136/bmj.312.7040.1177
Abstract
Biotechnology has opened entire new approaches to vaccine development, such as the rational and precise attenuation of bacteria and viruses to serve as live vaccines,1 the direct inoculation with plasmid DNA encoding protective antigens (“naked DNA” vaccines), and the microencapsulation of antigens to enhance immunogenicity and modulate the kinetics and type of immune response.2 Consequently, at various stages …Keywords
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