Stereospecific conversion of N,N-dimethylamphetamine into N-methylpseudoephedrine
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 10,p. 653-654
- https://doi.org/10.1039/c39850000653
Abstract
The pro-R hydrogen of (+)-N,N-dimethylamphetamine chromium tricarbonyl can be stereospecifically substituted via sequential treatment with BunLi and an electrophile, with rotation of configuration to give for example N-methylpseudoephedrine after decomplexation.Keywords
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