The time course of information-processing deficits in schizophrenia

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Abstract
A visual backward masking task was used to specify the time course of the information-processing dysfunction in 19 schizophrenic patients and 15 matched control patients using novel interstimulus intervals. The information-processing deficit in schizophrenic subjects occurred at interstimulus intervals of > 60 ms and < 500 ms. These data are compared with the result of evoked-potential and other psychophysiological studies. The visual-processing impairment is specific and time-linked rather than a reflection of the effects of gross psychopathology or medication in schizophrenic individuals.