A Case of Propylene Glycol Toxic Reaction Associated With Etomidate Infusion
- 1 November 1991
- journal article
- case report
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 151 (11) , 2297-2298
- https://doi.org/10.1001/archinte.1991.00400110137026
Abstract
For the treatment of postoperative seizures and prevention of brain edema, an etomidate drip was used in conjunction with phenytoin, diazepam, pentobarbital, and phenobarbital in a 70-year-old woman. During a period of 24 hours, the patient received in excess of 479 g of propylene glycol, which was present at 35% (vol/vol) concentration in the undiluted etomidate. The propylene glycol toxic reaction resolved after the infusion was stopped. (Arch Intern Med. 1991;151:2297-2298)Keywords
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