NEW GENERATION TISSUE VALVES - THEIR INVITRO FUNCTION IN THE MITRAL POSITION

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  • 1 January 1984
    • journal article
    • research article
    • Vol. 88  (4) , 573-582
Abstract
The in vitro function of 6 tissue valves from 4 manufacturers was assessed. One porcine bioprosthesis (Carpentier-Edwards supra-annular) and 5 pericardial valves (Edwards, Hancock, Ionescu-Shiley, Ionescu-Shiley low-profile and Mitral Medical Mitroflow) were tested. Valve function was measured in a pulse duplicator simulating conditions of sinus rhythm (60, 80 and 120 beats/min and stroke volume 70 ml) and supraventricular tachycardia (200 beats/min and stroke volume 30 ml). Under each of these test conditions, mean transvalvular pressure, regurgitation, and transvalvular energy loss were determined, and were used to compare valve function. The porcine valve showed the largest mean transvalvular pressure during forward flow. The total energy loss of this valve, however, was not the largest for the valves tested. The total transvalvular energy loss ranged between 3-12% for all valves and conditions. For all valves, energy loss and regurgitation were greatest during simulated tachycardia.