Combined Modality Treatment of Locally Advanced Lung Cancer
- 1 March 1998
- journal article
- research article
- Published by SAGE Publications in Tumori Journal
- Vol. 84 (2) , 259-269
- https://doi.org/10.1177/030089169808400227
Abstract
This paper describes the mechanisms of action of ionizing radiations combined with antineoplastic drugs. Some relevant drugs for the combined modality treatments of locally advanced lung cancer are reported. The meta-analyses including randomized trials comparing single agent (radiotherapy or chemotherapy) versus combined chemoterapy and radiotherapy in patients with unresectable non small cell lung cancer and limited small cell lung cancer are then reviewed. The clinical outcome in relation to different schedules of chemoradiotherapy (sequential, alternating and concurrent) is also focussed.Keywords
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