Leukemias and Vaginal Tumors Induced in Female Donryu Rats by Continuous Administration of l-Butyl-3,3-dimethyl-l-nitrosourea in the Drinking Water2
- 1 June 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 56 (6) , 1177-1181
- https://doi.org/10.1093/jnci/56.6.1177
Abstract
Three groups of Donryu rats, each consisting of 36 females, were continuously given solutions of l-butyl-3,3-dimethyl-l-nitrosourea as drinking water (400 ppm for group A, 200 ppm for group B, 100 ppm for group C). Of the 100 rats that survived at least 122 experimental days, 64 developed leukemia and 38 had vaginal tumors. Leukemias were preponderant in animals of groups A and B; vaginal tumors appeared in group C.Keywords
This publication has 1 reference indexed in Scilit:
- Hirntumoren bei Ratten nach oraler Gabe von N-Nitroso-N-methyl-harnstoffThe Science of Nature, 1967