DECIDUALIZATION AND OVUM-IMPLANTATION IN SPAYED MICE TREATED WITH OESTRIOL
- 1 February 1977
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 72 (2) , 181-185
- https://doi.org/10.1677/joe.0.0720181
Abstract
SUMMARY: Single injections of oestriol were partially effective in sensitizing the uterus to a decidual stimulus and inducing ovum-implantation in progesterone-treated spayed mice, whereas two injections (6 h apart) were fully effective. It seems that in the progestational uterus, as in the non-progestational organ, oestriol can induce a full oestrogenic response provided that its level in the target organ is maintained. It is also concluded that ovum-implantation is not triggered by some transient early effect of oestrogen, but requires about 12 h of sustained oestrogen action for its successful completion.This publication has 2 references indexed in Scilit:
- OESTRIOL, OESTRADIOL-17β AND THE PROLIFERATION AND DEATH OF UTERINE CELLSJournal of Endocrinology, 1976
- ENDOCRINE CONTROL OF ENDOMETRIAL SENSITIVITY DURING THE INDUCTION OF THE DECIDUAL CELL REACTION IN THE MOUSEJournal of Endocrinology, 1966