A Simple Protocol for Direct Reductive Amination of Aldehydes and Ketones Using Potassium Formate and Catalytic Palladium Acetate
- 26 February 2003
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 2003 (4) , 0555-0557
- https://doi.org/10.1055/s-2003-37509
Abstract
A method for direct reductive amination of aldehydes and ketones, including α,β-unsaturated carbonyl compounds, has been developed, which requires potassium formate as reductant and palladium acetate as catalyst. Suitable amines include both primary and secondary aliphatic and aromatic amines.Keywords
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