Psychiatric symptoms associated with Alzheimer's disease
- 1 February 1990
- journal article
- research article
- Published by American Psychiatric Association Publishing in The Journal of Neuropsychiatry and Clinical Neurosciences
- Vol. 2 (1) , 28-33
- https://doi.org/10.1176/jnp.2.1.28
Abstract
A retrospective chart review was undertaken to assess the prevalence of specifically defined psychiatric symptoms in 217 outpatients with clinically probable Alzheimer's disease. A weak but significant correlation was found between Alzheimer's disease and suspiciousness and paranoia (reported by 35.5% of patients), delusions (30%), and formed visual hallucinations (18.4%). Mild depressive symptoms, such as sad affect, hopelessness, and helplessness were reported by 40.6% of patients, anxiety and fearfulness by 30.9%, and aggressive acts by 24.9%. Psychotropic medications used to manage these symptoms included antipsychotics, in 11.5% of patients, anxiolytics, in 9.2%, and antidepressants, in 7.4%.Keywords
This publication has 14 references indexed in Scilit:
- Major Depression in Primary DementiaArchives of Neurology, 1988
- The neuropathology of aminergic nuclei in Alzheimer's diseaseAnnals of Neurology, 1988
- Neuroleptic malignant syndrome and lethal catatoniaAmerican Journal of Psychiatry, 1987
- Assessing Dementia. Part II: Clinical, Functional, Neuropsychological and Social IssuesAustralian & New Zealand Journal of Psychiatry, 1987
- Neuropsychiatric Aspects of Multi-infarct Dementia and Dementia of the Alzheimer TypeArchives of Neurology, 1987
- Delusions and the psychopathology of the elderly with dementiaActa Psychiatrica Scandinavica, 1985
- Depression in Patients Referred to a Dementia ClinicArchives of Neurology, 1985
- Preliminary report on affective symptoms in the early stages of senile dementia of the Alzheimer typeAmerican Journal of Psychiatry, 1983
- Coexistence of cognitive impairment and depression in geriatric outpatientsAmerican Journal of Psychiatry, 1982
- “Mini-mental state”Journal of Psychiatric Research, 1975