A Convenient Method for the Preparation of Secondary Propargylic Ethers. The Reaction of Acetals with 1-Trimethylsilylalkynes Promoted by the Combined Use of Catalytic Amounts of Tin(IV) Chloride and Zinc Chloride
- 5 October 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 16 (10) , 1975-1978
- https://doi.org/10.1246/cl.1987.1975
Abstract
In the coexistence of catalytic amounts of SnCl4 and ZnCl2, acetals undergo a coupling with 1-trimethylsilylalkynes in good yields to give secondary propargylic ethers, which are also directly produced from aldehydes by the reaction with alkoxytrimethylsilanes and 1-trimethylsilylalkynes under the same conditions.Keywords
This publication has 2 references indexed in Scilit:
- Asymmetric synthesis via acetal templates. 4. Reactions with silylacetylenic compounds. Formation of chiral propargylic alcoholsJournal of the American Chemical Society, 1983
- Titanium Tetrachloride in Organic Synthesis [New synthetic methods (21)]Angewandte Chemie International Edition in English, 1977