RETICULAR DYSGENESIS - REPORT OF 2 BROTHERS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 38  (3) , 615-620
Abstract
Two brothers had marked leukopenia, lymphopenia, no immunological respnse to infections (no Ig [immunoglobulin] production, negative PHA [phytohemagglutinin] response and very low number of T [thymus-derived] and B [bone marrow-derived] lymphocytes in peripheral blood) and hypocellular marrow. They died at 12 and 8 days of life with infection of (Escherichia coli and Klebsiella, respectively).