Studies of the binding of chromium(III) complexes to phosphate groups of adenosine triphosphate
- 1 May 1991
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 12 (5) , 921-926
- https://doi.org/10.1093/carcin/12.5.921
Abstract
The binding of a number of chromium complexes to ATP has been studied by 31P NMR spactroscopy. The results are consistent with the formation of outer-sphere complexes between ATP and the chromum species. The magnitude of the binding constant has been determine as ∽ 500 mol−1 dm3 (pH = 7.00) for the interaction of trisethylenediamine chromium (III) with ATP. Under our exprimental conditions no NMR signals are observed from complexes in which chromium (III) and glutathione or ATP is probably not a significant factor in determing the toxicity of chromium (III) complexes.Keywords
This publication has 0 references indexed in Scilit: