Preparation of N.C.A. [18F]‐CH2BrF via aminopolyether supported nucleophilic substitution
- 1 June 1986
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 23 (6) , 587-595
- https://doi.org/10.1002/jlcr.2580230604
Abstract
A complex of the macrocyclic aminopolyether Kryptofix® 2.2.2. and potassium carbonate was used to synthesize [18F]‐CH2BrF from dibromomethane. At the no‐carrier‐added level the nucleophilic 18F‐for‐Br exchange gives rise to a corrected radiochemical yield up to 62%.Keywords
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