The Stimulating Action of Copper on Erythropoiesis

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Abstract
The feeding of evaporated milk to normal rats produces a fall in hemoglobin without the corresponding drop in the erythrocyte count that occurs when raw milk is the sole article of diet. When copper without iron is fed as a supplement to raw milk, results similar to those with evaporated milk are obtained, indicating that the copper in the evaporated milk is responsible for the temporary maintenance of a high erythrocyte count. When given as a supplement to the milk diet of anemic rats, copper ranging in amounts from 0.025 mg. to 0.5 mg. daily shows a definite erythropoietic action without any influence on hemoglobin formation.
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