Metabolism of Pyrene and Chrysene in Epithelial Human Bronchial and Hamster Lung Cells
- 1 February 1990
- journal article
- research article
- Published by Taylor & Francis in International Journal of Environmental Analytical Chemistry
- Vol. 38 (2) , 221-230
- https://doi.org/10.1080/03067319008026929
Abstract
The metabolism of pyrene and chrysene in epithelial human bronchial and in hamster lung cells has been studied and found to be very similar in both systems, although it differs from that observed in rat lung microsomes. Metabolite profiles have been analyzed by means of capillary GC and by GC/MS.Keywords
This publication has 8 references indexed in Scilit:
- Comparison of chrysene metabolism in epithelial human bronchial and Syrian hamster lung cellsCancer Letters, 1987
- Capillary Gas Chromatographical Analysis and Mass Spectrometric Identification of Polycyclic Aromatic Hydrocarbon Metabolites from Biological MaterialsReviews in Analytical Chemistry, 1987
- Growth inhibition and transformation of a human fetal tracheal epithelial cell line by long-term exposure to diethylnitrosamineCarcinogenesis: Integrative Cancer Research, 1985
- Formation of carcinogenic and inactive chrysene metabolites by rat liver microsomes of various monooxygenase activitiesArchives of Toxicology, 1982
- A fetal respiratory epithelial cell line for studying some problems of transplacental carcinogenesis in Syrian golden hamstersZeitschrift für Krebsforschung und Klinische Onkologie, 1982
- Comparison of toxic and transforming effects of ten environment‐related polycyclic hydrocarbons, including benzo [a] pyrene, on Fetal Hamster Lung Cell CulturesJournal of Applied Toxicology, 1982
- The metabolism of pyrene by rat liver microsomes and the influence of various mono-oxygenase inducersXenobiotica, 1982
- Glass-Capillary-Gas Chromatography/Mass Spectrometry Data of Mono- and Poly-hydroxylated Benz[α]anthracene. Comparison with Benz[α]anthracene Metabolites from Rat Liver MicrosomesHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1981