1-(Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinol esters. New potent antiamebic agents
- 1 May 1979
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 22 (5) , 599-601
- https://doi.org/10.1021/jm00191a031
Abstract
A series of 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinols and certain 0-acyl derivatives thereof were prepared and are potent antiamebic agents in the Entamoeba criceti infected hamster model. Compounds were compared with etichlordifene and diloxamide and 1 of them, 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline, was selected for human trial.This publication has 1 reference indexed in Scilit: