Discovery of New Multi Component Reactions with Combinatorial Methods
- 1 March 1999
- journal article
- new tools-in-synthesis
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1999 (3) , 366-374
- https://doi.org/10.1055/s-1999-2612
Abstract
The discovery of novel chemical reactions or reaction sequences that are able to generate useful chemical products may be regarded as the heart of organic chemistry. We present here concepts and methods on how to find and explore new multi component reactions, especially with automated combinatorial methods. This "combinatorial reaction finding" provides also a powerful tool to the understanding of the rules of organic chemistry, especially structure-reactivity relationships.Keywords
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