INTRACELLULAR SPIRAL INCLUSIONS IN CEREBRAL CELL PROCESSES IN CREUTZFELDT-JAKOB DISEASE

  • 1 January 1981
    • journal article
    • research article
    • Vol. 40  (1) , 1-8
Abstract
EM examination of brain biopsy specimens from 2 patients with Creutzfeldt-Jakob disease revealed the presence of intracellular membranous spiral inclusions in the processes of cortical cells. These inclusions, 375-660 nm in length and 50-88 nm in width, resemble similar structures reported in a patient with the same disease by Bastian and in a 2nd patient by Gray et al. These inclusions bear close morphologic resemblance to spiroplasma organisms, a wall-free prokaryote known to cause a slow-virus-like disorder in mice.

This publication has 0 references indexed in Scilit: