Swelling of Capillary Endothelial Cells Contributes to Traumatic Hemorrhagic Shock-Induced Microvascular Injury: A Morphologic and Morphometric Analysis
- 1 January 1994
- journal article
- research article
- Published by S. Karger AG in International Journal of Microcirculation
- Vol. 14 (1-2) , 45-49
- https://doi.org/10.1159/000178205
Abstract
The endothelial cell (EC) response during the first 2 h after traumatic hemorrhagic shock (THS) was analyzed in the rat mesentery by electron microscopy. Using a computer-assisted image analysis system, we interactively measured THS-induced changes of the area and the mean height of EC as well as the number of swollen EC occluding the capillary lumen. Analysis distinguished between capillaries presenting with the lumen blocked by corpuscular blood cells and capillaries with an open lumen. THS resulted in a significant increase in EC height of capillaries with an open lumen, but not of capillaries with lumen blocked by blood cells when compared with the control group (pKeywords
This publication has 0 references indexed in Scilit: