Prehepatic Total Parenteral Nutrition in the Chair‐adapted Primate

Abstract
The relative efficacy of prehepatic and central venous infusion of total parenteral nutrition (TPN) was evaluated in a chair-adapted primate model. Four adult male monkeys (Macaca fascicularis) underwent surgical placement of a silastic catheter in both the portal vein (PV) and superior vena cava (SVC). Following recovery (10 days), each animal received two courses of TPN (100 kcal and 4 g of protein/kg/day) for 10 days each via the PV and SVC in an alternating crossover manner.