Induction of labor

1 January 1985

journal article
research article
Published by Wiley in Acta Obstetricia et Gynecologica Scandinavica

Vol. 64 (2) , 157-161
https://doi.org/10.3109/00016348509154710

Abstract

In a double-blind randomized controlled study of 300 women, 150 primiparas and 150 multiparas, induction of labor by means of vaginal suppositories containing 3 mg prostaglandin E₂ (PGE₂) was compared with the conventional method of intranasal oxytocin and with a combined method of 3 mg PGE₂ vaginal suppositories alternating with intranasal oxytocin. In the PGE₂ group the intensity of delivery was significantly greater than in the oxytocin group, among both primiparas and multiparas and among the patients with ripe and unripe cervix. The efficiency of the combined treatment could no be evaluated because of the high intensity of delivery during the first 24 hours. There were no maternal side effects, and no significant difference in the frequencies of failed induction and cesarean section.

Keywords

This publication has 1 reference indexed in Scilit:

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples
British Journal of Cancer, 1977