Nine-Year Surveillance of Methicillin-ResistantStaphylococcus aureusin a Hospital Suggests Instability ofmecADNA Region in an Epidemic Strain

Open Access
Publisher Website
Google Scholar
Abstract
The distributions of the antibiotic resistance patterns in a population of Staphylococcus aureus isolates from a teaching hospital were studied over a 9-year period. The results indicate the existence of successive major epidemic methicillin-resistant strains and the emergence of a methicillin-susceptible strain with an unusual resistance pattern. Our findings suggest that this methicillin-susceptible S. aureus strain could be derived from the dominant gentamicin-susceptible methicillin-resistant S. aureus strain with the loss of a 40-kb DNA fragment.

This publication has 33 references indexed in Scilit: