The isolation of androst-16-en-3α-ol from women's urine

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Abstract
Enzymic hydrolysis of a partially purified "pregnanediol-like glucuronide" fraction from the urine of women in the "follicular" phase of the menstrual cycle gave a mixture from which was isolated androst-16-en-3 alpha-ol and pregnane-3 alpha : 20 alpha-diol. The amt. of the latter substance obtained indicated an original concn. of the order of 0.4 mg./l. of the urine, whilst the androstenol might have been present in amts. of 0.2-0.3 mg./l. The musk-smelling androst-16-en-3 alpha-ol is thus truly characteristic of the (hydrolysed) urine of men and women.