Enzymatic synthesis of optically active 2-carbamoyl-oxymethyl-1,4-dihydropyridines, (R)-(+)- and (S)-(−)-NB 818

This publication has 9 references indexed in Scilit:

• Lipase-catalyzed enantioselective hydrolysis of 4-alkyl-1,4-dihydropyridine derivatives: synthesis of (+)- and (-)-methyl 2-(phenylthio)ethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate(PCA 4248).
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1992
• Acyloxymethyl as an activating group in lipase-catalyzed enantioselective hydrolysis. A versatile approach to chiral 4-aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylates.
  Tetrahedron Letters, 1991
• Synthesis and pharmacological effects of optically active 2-(4-(4-benzhydryl-1-piperazinyl)phenyl)-ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate hydrochloride.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1991
• Studies on Nilvadipine. I. Synthesis and Structure-Activity Relationships of 1,4-Dihydropyridines Containing Novel Substituents at the 2-Position.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1991
• The synthesis of 2-substituted-1,4-dihydropyridines
  Tetrahedron, 1989
• Synthesis and biological activities of optical isomers of 2-(4-diphenylmethyl-1-piperazinyl)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (manidipine) dihydrochloride.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1989
• Long-acting dihydropyridine calcium antagonists. 1. 2-Alkoxymethyl derivatives incorporating basic substituents
  Journal of Medicinal Chemistry, 1986
• Synthesis of optically active 2-(N-benzyl-N-methylamino)ethyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (nicardipine).
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1980
• Dihydropyridine, eine neue Gruppe stark wirksamer Coronartherapeutika
  The Science of Nature, 1971