Countercurrent Chromatography: Liquid-Liquid Partition Chromatography without Solid Support
- 16 January 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 167 (3916) , 281-283
- https://doi.org/10.1126/science.167.3916.281
Abstract
The liquid-liquid partition chromatographic system reported here involves a long helix of narrow-bore tubing. When the coiled tube is filled with one phase of a two-phase system and fed with the other phase, phase-interchange takes place in each turn of the coil, leaving a segment of the former phase as the stationary phase. Consequently, solutes present in either phase are subjected to a multistep partition process. The column efficiency, estimated on a separation of dinitrophenyl amino acids, is comparable to that of gas chromatography.Keywords
This publication has 3 references indexed in Scilit:
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- The Coil Planet CentrifugeNature, 1966
- Partial Hydrolysis Studies with Bacitracin AJournal of the American Chemical Society, 1955