Cholesteryl ester hydrolase activity in human symptomatic atherosclerosis
- 1 December 1980
- Vol. 15 (12) , 1019-1022
- https://doi.org/10.1007/bf02534317
Abstract
Acid cholesteryl ester hydrolase (CEH) activity was assayed in mononuclear cells of patients with symptomatic atherosclerosis (transient ischemic attacks, TIA) and in age-matched controls showing no evidence of atherosclerosis. The acid CEH level of TIA patients was significantly lower than that of controls (1074±128 vs 2113±255 pmol/mg P/hr, mean±SE). Neither mononuclear cell nor plasma cholesterol and cholesteryl ester concentrations differed significantly between atherosclerotic and control groups. TIA women had lower mononuclear cell concentrations of free sholesterol than men.Keywords
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