Maternal Periodontitis and Prematurity. Part I: Obstetric Outcome of Prematurity and Growth Restriction

Top Cited Papers
Publisher Website
Google Scholar
Abstract
Oral Conditions and Pregnancy (OCAP) is a 5‐year prospective study of pregnant women designed to determine whether maternal periodontal disease contributes to the risk for prematurity and growth restriction in the presence of traditional obstetric risk factors. Full‐mouth periodontal examinations were conducted at enrollment (prior to 26 weeks gestational age) and again within 48 hours postpartum to assess changes in periodontal status during pregnancy. Maternal periodontal disease status at antepartum, using a 3‐level disease classification (health, mild, moderate‐severe) as well as incident periodontal disease progression during pregnancy were used as measures of exposures for examining associations with the pregnancy outcomes of preterm birth by gestational age (GA) and birth weight (BW) adjusting for race, age, food stamp eligibility, marital status, previous preterm births, first birth, chorioamnionitis, bacterial vaginosis, and smoking. Interim data from the first 814 deliveries demonstrate that maternal periodontal disease at antepartum and incidence/progression of periodontal disease are significantly associated with a higher prevalence rate of preterm births, BW Ann Periodontol 2001;6:164‐174.

This publication has 25 references indexed in Scilit: