Novel prodrug approach to amprenavir-based HIV-1 protease inhibitors via O→N acyloxy migration of P1 moiety
- 14 June 2003
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 13 (15) , 2523-2526
- https://doi.org/10.1016/s0960-894x(03)00463-3
Abstract
No abstract availableKeywords
This publication has 5 references indexed in Scilit:
- Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 proteaseBioorganic & Medicinal Chemistry Letters, 2002
- New water-soluble prodrugs of HIV protease inhibitors based on O→N intramolecular acyl migrationBioorganic & Medicinal Chemistry, 2002
- Synthesis of 4‐chloro‐7‐ethoxy‐2(3H)‐benzoxazolone‐6‐carboxylic acidJournal of Heterocyclic Chemistry, 1996
- Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzymeJournal of the American Chemical Society, 1995
- Formal total synthesis of erythromycin A. Part III. Synthesis of Woodward's carbamate key intermediate from a 1,7-dioxaspiro[5.5]undecane derivative of erythronolide ACanadian Journal of Chemistry, 1985