Hyperacute Rejection in Human-Kidney Allografts — Shwartzman or Arthus Reaction?

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Abstract
The course of three patients indicated that both types of reaction, Shwartzman and Arthus-like, can occur in hyperacute rejection of human-kidney allografts and that the late histologic appearances may be indistinguishable. In the first patient hyperacute failure of the kidney occurred in four hours, in association with the development of a bleeding diathesis. Sequential histologic appearances were those of progressive fibrin deposition resembling a generalized Shwartzman reaction.