Urea in the Seminiferous Tubule: Evidence for Active Transport
- 1 April 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 20 (3) , 511-515
- https://doi.org/10.1095/biolreprod20.3.511
Abstract
Nephrectomized male rats were infused i.v. with [14C]-urea. The amount of radioactivity in subsequent micropuncture samples of cauda epididymal tubule (CET) fluids demonstrated a restricted movement of [14C]-urea into the CET. In the seminiferous tubules (SNT), radioactivity from [14C]-urea became higher than in blood plasma. 2,4-Dinitrophenol and ouabain inhibited this uphill movement of [14C]-urea, thus giving evidence for active transport of urea into the rat SNT.This publication has 3 references indexed in Scilit:
- Hyperosmolality in Intraluminal Fluids from Hamster Testis and Epididymis: A Micropuncture StudyScience, 1977
- Urea secretion by the straight segment of the proximal tubule.Journal of Clinical Investigation, 1976
- Micropuncture Studies of the Blood-Seminiferous Tubule Barrier11Biology of Reproduction, 1976