High-Speed Detection of Blood-borne Hepatitis C Virus RNA by Single-Tube Real-Time Fluorescence Reverse Transcription-PCR with the LightCycler
- 1 December 2000
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 46 (12) , 1987-1989
- https://doi.org/10.1093/clinchem/46.12.1987
Abstract
Hepatitis C virus (HCV) has been identified as the agent responsible for the vast majority of cases of posttransfusion non-A, non-B hepatitis. Although generally asymptomatic, ∼85% of the infections become chronic with a wide spectrum of outcomes (1).Keywords
This publication has 8 references indexed in Scilit:
- Second Generation of the Automated Cobas Amplicor HCV Assay Improves Sensitivity of Hepatitis C Virus RNA Detection and Yields Results That Are More Clinically RelevantJournal of Clinical Microbiology, 1999
- Real-time detection system for quantification of hepatitis C virus genomeGastroenterology, 1999
- High-Throughput Real-Time Reverse Transcription-PCR Quantitation of Hepatitis C Virus RNAJournal of Clinical Microbiology, 1999
- Continuous Fluorescence Monitoring of Rapid Cycle DNA AmplificationBioTechniques, 1997
- The Risk of Transfusion-Transmitted Viral InfectionsNew England Journal of Medicine, 1996
- Detection of hepatitis C virus RNA by a combined reverse transcription-polymerase chain reaction assayJournal of Clinical Microbiology, 1993
- Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distributionJournal of Virology, 1992
- An immunoassay for specific amplified HCV sequencesJournal of Virological Methods, 1991