Clinical Comparison of Two Agents Used In Brain Scanning

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Abstract
Sixty-three patients with suspected intracranial lesions were scanned with both chlormerodrin Hg 203 (Neohydrin) and radio-iodinated serum albumin (Risa). Scans were read as unknowns and were compared for accuracy and overall quality. Results in 23 patients with tumors, two with abscesses and seven with hematomas, were nearly identical. Both agents correctly localized 78% or missed the same neoplasms. There were no false-positive studies in 31 patients, without evidence of intracranial space-taking lesions. This study suggests that brain scanning be performed initially with chlormerodrin Hg 203, largely because of the temporal convenience. If interpretation of the chlormerodrin Hg 203 scans is equivocal, scanning with radio-iodinated serum albumin at 24 and 48 hours is recommended.

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