Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents

This publication has 26 references indexed in Scilit:

• Pharmacological profile of parecoxib: a novel, potent injectable selective cyclooxygenase-2 inhibitor
  European Journal of Pharmacology, 2004
• Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors
  Journal of Medicinal Chemistry, 2003
• 6-Alkyl, alkoxy, or alkylthio-substituted 3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors
  Bioorganic & Medicinal Chemistry Letters, 2003
• Risk of Cardiovascular Events Associated With Selective COX-2 Inhibitors
  JAMA, 2001
• 4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2
  Journal of Medicinal Chemistry, 2000
• Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy
  British Journal of Pharmacology, 1999
• Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
  Proceedings of the National Academy of Sciences, 1999
• Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
  Journal of Medicinal Chemistry, 1997
• 1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents
  Journal of Medicinal Chemistry, 1995
• Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
  Proceedings of the National Academy of Sciences, 1993