RANITIDINE FOR DUODENAL-ULCER - COMPARISON OF ONE-DOSE AND 2-DOSE ADMINISTRATION
- 10 May 1986
- journal article
- research article
- Vol. 116 (19) , 637-641
Abstract
In a Swiss multicenter double-blind trial ranitidine was given in doses of 300 mg nocte and 150 mg b.d. for the treatment of duodenal ulcer. Ninety-seven patients with endoscopically proven ulcer were treated for four, and in cases of non-healing for eight weeks. Cumulative healing rates with 300 mg and 2 .times. 150 mg were 77% and 78% after four weeks and 90% and 94% after eight weeks, respectively. Sixty and 65% of the patients were asymptomatic after four weeks. Smoking did not adversely affect healing. Thus, ranitidine in a dose of 300 mg nocte is as effective as ranitidine in a dose of 150 mg b.d. in the treatment of duodenal ulcer.This publication has 13 references indexed in Scilit:
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