Rapid antimicrobial susceptibility testing of Gram-negative clinical isolates with the AutoMicrobic system

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Abstract
Comparisons of the antimicrobial susceptibility patterns of clinical isolates of the family Enterobacteriaceae and Pseudomonas aeruginosa were made by using Kirby-Bauer disc diffusion, the MicroMedia system broth microdilution and the AutoMicrobic system. The Kirby-Bauer system compared favorably with the MicroMedia system (95% essential correlation with 90% complete agreement). The AutoMicrobic system also compared favorably with both the Kirby-Bauer system (93% essential correlation with 87% complete agreement) and the MicroMedia system (97% essential correlation with 85% complete agreement). Thus, the AutoMicrobic system results are comparable to those of the MicroMedia and the Kirby-Bauer systems. The AutoMicrobic system offers a more rapid system (6-10 h), than the traditional systems, without sacrificing accuracy (16-24 h).