MELANIN PRODUCTION IN SKIN
- 1 June 1945
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology and Syphilology
- Vol. 51 (6) , 376-383
- https://doi.org/10.1001/archderm.1945.01510240022005
Abstract
An earlier report1 dealt with the influence of protoplasmic poisons, such as potassium cyanide and sodium fluoride, and of alkalinity on the Meirowsky phenomenon (the increase in epidermal pigment in excised or cadaver skin when incubated at 37 C. and higher or on exposure to ultraviolet rays). These poisons served to accelerate the formation of pigment. It was further reported that in the experiment in which the solution containing the skin sections was overlaid with liquid petrolatum there was demonstrated an increased acceleration in pigment production. On the basis of this evidence it was suspected that atmospheric oxygen possibly was not required for the production of this phenomenon. Earlier investigators of this phenomenon all came to the conclusion that atmospheric oxygen was required for its elicitation. The most recent and comprehensive studies of this problem, by Miescher and Minder2 and, incidentally published beforeThis publication has 1 reference indexed in Scilit:
- HISTOCHEMICAL OBSERVATIONS ON MELANIN PRODUCTION IN THE SKINArchives of Dermatology, 1942