Rhodamine 123 Requires Carrier-Mediated Influx for Its Activity as a P-Glycoprotein Substrate in Caco-2 Cells
- 1 January 2003
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 20 (8) , 1192-1199
- https://doi.org/10.1023/a:1025096930604
Abstract
Purpose. The purpose of this work was to elucidate transport pathways of the P-glycoprotein (P-gp) substrates rhodamine 123 (R123) and doxorubicin across Caco-2 cells. Methods.Experiments were...Keywords
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