Molecular basis of bluetongue virus neutralization
- 1 December 1983
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 48 (3) , 627-632
- https://doi.org/10.1128/jvi.48.3.627-632.1983
Abstract
Molecular and serological analyses of bluetongue virus serotypes 10 and 11 and their intertype reassortants indicate that the viral RNA segment L2 codes for the serotype-specific antigen. Individual RNA segments of parental and reassortant viruses were characterized by oligonucleotide fingerprint analyses. Analyses of their virion polypeptides by Cleveland peptide mapping demonstrated that the L2 gene segregated colinearly with the viral P2 protein, implicating it as the antigen that is responsible for the viral serotype specificity.This publication has 15 references indexed in Scilit:
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