Optical isomers of the H1 antihistamine terfenadine: synthesis and activity
- 1 January 1991
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 1 (8) , 387-390
- https://doi.org/10.1016/s0960-894x(00)80261-9
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- Optical isomers of rocastine and close analogs: synthesis and H1 antihistaminic activity of its enantiomers and their structural relationship to the classical antihistaminesJournal of Medicinal Chemistry, 1991
- Comparative study of central and peripheral histamine-H1 receptor binding in vitro and ex vivo of non-sedating antihistamines and of noberastine, a new agentDrug Development Research, 1991
- Torsades de pointes occurring in association with terfenadine useJAMA, 1990
- TerfenadineDrugs, 1990
- High affinity, saturable [3H]mepyramine binding sites on rat liver plasma membrane do not represent histamine H1-receptorsBiochemical Pharmacology, 1989
- Chiral synthesis via organoboranes. 14. Selective reductions. 41. Diisopinocampheylchloroborane, an exceptionally efficient chiral reducing agentJournal of the American Chemical Society, 1988
- 2-Chloro-4(R),5(R)-dimethyl-2-oxo-1,3,2-dioxaphospholane, a new chiral derivatizing agentThe Journal of Organic Chemistry, 1984
- HETEROGENEITY OF HISTAMINE Hi‐RECEPTORS: SPECIES VARIATIONS IN [3H]MEPYRAMINE BINDING OF BRAIN MEMBRANESJournal of Neurochemistry, 1979