The Hereditary Renal Diseases

Abstract
THE past two decades have seen rapid growth of knowledge of clinical and biochemical genetics, and of the mechanisms by which genetically determined diseases occur. It is not surprising, then, that the number of diverse renal diseases now known to be hereditary has increased steadily from a few1 to 30 or more.2 , 3 At the same time, understanding of the pathogenesis of some of these disorders has increased. Growth in understanding has been variable, however, and has occurred mainly in the area of the physiology of several abnormalities of renal tubular function. Considerably less is known about the hereditary diffuse anatomic . . .