INVITRO BINDING OF 2-ACETAMINOFLUORENE TO RNA AND PROTEIN WITH RAT-LIVER MICROSOMES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 69  (4) , 533-538
Abstract
Covalent binding of [the carcinogen] 2-acetaminofluorene[9-14C] with exogenous Torula yeast RNA and endogenous protein was investigated in a rat liver microsome system in vitro. Ring-hydroxylated product other than N-hydroxy-2-acetaminofluorene was suggested as a possible metabolite for binding.

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