Principles of DNA separation with capillary electrophoresis
- 26 February 2001
- journal article
- review article
- Published by Wiley in Electrophoresis
- Vol. 22 (4) , 629-643
- https://doi.org/10.1002/1522-2683(200102)22:4<629::aid-elps629>3.0.co;2-s
Abstract
During the last decade, capillary electrophoresis (CE) of DNA has undergone rapid development. This improvement was especially important for DNA sequencing, where CE has now become a standard method facilitating to decipher several genomes within a very short time. Here, we give a review of the fundamentals of DNA separation in CE and the major factors influencing the performance.Keywords
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