Single-nucleotide evolutionary constraint scores highlight disease-causing mutations
Open Access
- 1 April 2010
- journal article
- research article
- Published by Springer Nature in Nature Methods
- Vol. 7 (4) , 250-251
- https://doi.org/10.1038/nmeth0410-250
Abstract
No abstract availableKeywords
This publication has 6 references indexed in Scilit:
- Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomesGenome Research, 2010
- Exome sequencing identifies the cause of a mendelian disorderNature Genetics, 2009
- Targeted capture and massively parallel sequencing of 12 human exomesNature, 2009
- Distribution and intensity of constraint in mammalian genomic sequenceGenome Research, 2005
- Listening to silence and understanding nonsense: exonic mutations that affect splicingNature Reviews Genetics, 2002
- Prediction of deleterious human allelesHuman Molecular Genetics, 2001