Accumulation and Removal of Hg203 in Different Regions of the Rat Brain
- 1 November 1978
- journal article
- research article
- Published by Cambridge University Press (CUP) in Canadian Journal of Neurological Sciences
- Vol. 5 (4) , 397-400
- https://doi.org/10.1017/s0317167100024161
Abstract
SUMMARY: We have studied the brain regional distribution of methyl mercury following intravenous administration of CH3203HgCl in rat. Early peak levels were obtained in cerebellum, medulla oblongata and midbrain. The efficacy of removal of 203Hg by different chelators is also region dependent. The most efficient chelator for brain mercury proved to be mesodimercaptosuccinic acid.Keywords
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