ARRHENOBLASTOMA DURING PREGNANCY

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Abstract
Arrhenoblastoma is a rare complication of pregnancy. A case of fatal nonvirilizing arrhenoblastoma in a pregnant adolescent, the 3rd such case to appear in the literature, is discussed. Fifteen cases of arrhenoblastoma in pregnancy that appeared in the recent literature are reviewed; 87% of these tumors were virilizing. When virilization is absent the diagnosis is difficult. Among the more common presenting symptoms are weight loss, nausea and vomiting, abdominal pain and a palpable abdominal mass. Arrhenoblastoma occurring during pregnancy has a 31% maternal mortality, 44% rate of malignancy and a 50% perinatal mortality.