The sperm centrosome during fertilization in mammals: implications for fertility and reproduction
- 1 January 1995
- journal article
- review article
- Published by CSIRO Publishing in Reproduction, Fertility and Development
- Vol. 7 (4) , 747-754
- https://doi.org/10.1071/rd9950747
Abstract
This article reviews the recent discoveries that: (1) nearly all mammals, including humans, inherit their centrosomes from their fathers; and (2) some sperm are ineffective in organizing the microtubules essential for effecting genomic union during fertilization, leading to the speculation that these sperm have centrosome defects. In addition, the molecular dissection and reconstitution of the human sperm centrosome in vitro is presented.Keywords
This publication has 0 references indexed in Scilit: