High serum levels of CA125 and interleukin‐6 in a patient with Ki‐1 lymphoma
- 1 August 1997
- journal article
- case report
- Published by Wiley in British Journal of Haematology
- Vol. 98 (2) , 450-452
- https://doi.org/10.1046/j.1365-2141.1997.2383054.x
Abstract
We report a 53-year-old-man with an aggressive Ki-1 lymphoma who had high serum CA125, a marker protein of the epithelial ovarian cancer, and interleukin-6 (IL-6) concentrations. Both CA125 and IL-6 levels decreased after chemotherapy and elevated with disease progression. The patient's lymphoma cells obtained before chemotherapy grew continuously in vitro, were IL-6 dependent and were found to secrete CA125 in culture medium. These results indicate that CA125 can be secreted by Ki-1 lymphoma cells and IL-6 may promote the growth of Ki-1 lymphoma cells.Keywords
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