Amoxapine Neurotoxicity: A Case Report with Long-Term Follow-up

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Abstract
A case of amoxapine (Asendin) overdose, in a 24-year-old female, is presented. The manifestations of amoxapine ingestion in this case are dissimilar to those of previously described tricyclic antidepressant (TCA) overdoses, and to those previously described for amoxapine. The signs and symptoms of TCA toxicity are discussed and contrasted with observations of this case. Impressions from this case indicate that amoxapine and other dibenzoxazepine derivatives possess a significantly different and greater toxic potential than other TCA agents.