OCCURRENCE OF ANTIBODIES TO SINGLE-STRANDED-DNA IN ANA NEGATIVE PATIENTS
- 1 January 1979
- journal article
- research article
- Vol. 37 (2) , 190-195
Abstract
Patients (5) with clinical features of a connective tissue disease most suggestive of systemic lupus erythematosus had a negative ANA [anti-nuclear antibody] by conventional screening at 1/20 dilution on mouse liver. Significant titers of antibodies to single-stranded DNA were detected using a double antibody radioimmunoassay. Certain patients have antibodies to DNA restricted to single-stranded determinants as detected by radioimmunoassay with single-stranded DNA as antigen and a negative ANA test.This publication has 8 references indexed in Scilit:
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